Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360406 | 0.94 | F10 (0.48) | F10RAB9ANPC1 | |
| SCHEMBL7357718 | 0.87 | F10 (0.45) | F10ALDH1A1RAB9ANPC1CHRM1 | |
| SCHEMBL7379779 | 0.87 | KCNMA1 (0.49) | ALDH1A1RAB9ANPC1KDM4ECHRM1 | |
| SCHEMBL6109506 | 0.82 | F10 (0.51) | POLBF10ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7362651 | 0.80 | F10 (0.47) | F10 | |
| SCHEMBL7360970 | 0.80 | F10 (0.46) | F10 | |
| SCHEMBL6107653 | 0.79 | F10 (0.52) | POLBF10ALDH1A1RAB9ANPC1 | |
| SCHEMBL7359375 | 0.77 | F10 (0.44) | F10 | |
| SCHEMBL7358439 | 0.76 | F10 (0.51) | POLBF10ALDH1A1RAB9ANPC1 | |
| SCHEMBL6106814 | 0.75 | F10 (0.48) | F10ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |