Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 6/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553174 | 0.89 | PTGES (0.43) | STSPTGESALOX5NTRK1EGFR | |
| SCHEMBL8557168 | 0.89 | GAA (0.44) | STSPTGESALOX5NTRK1ALDH1A1 | |
| SCHEMBL8554369 | 0.86 | GAA (0.46) | PTGESALOX5NTRK1ALDH1A1LMNA | |
| SCHEMBL8556673 | 0.85 | PTGES (0.40) | STSPTGESALOX5NTRK1EGFR | |
| SCHEMBL8553246 | 0.82 | NTRK1 (0.39) | PTGESALOX5NTRK1ALDH1A1LMNA | |
| SCHEMBL8552919 | 0.82 | FPR1 (0.44) | PTGESALOX5NTRK1LMNASMN1; SMN2 | |
| SCHEMBL1984012 | 0.81 | NTRK1 (0.48) | PTGESALOX5NTRK1ALDH1A1LMNA | |
| SCHEMBL8555845 | 0.81 | LMNA (0.47) | PTGESALOX5NTRK1ALDH1A1LMNA | |
| SCHEMBL8552075 | 0.79 | FPR1 (0.41) | PTGESALOX5NTRK1ALDH1A1LMNA | |
| SCHEMBL8556018 | 0.78 | LMNA (0.48) | NTRK1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000053649-A | SULFONYLUREIDOPYRAZOLE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 2000-02-22 | — | — | JP | disclosed |