Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158354 | 0.87 | PTGDR (0.54) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 | |
| SCHEMBL14721936 | 0.82 | LMNA (0.47) | LMNATSHRSMN1; SMN2GAAHTT | |
| 2,4-Dichlorophenoxyacetic Acid, Methyl Ester SCHEMBL5004223 | 0.81 | MAPT (0.70) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 | |
| SCHEMBL11156651 | 0.81 | PTGDR (0.49) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 | |
| SCHEMBL4887579 | 0.80 | CYP1A2 (0.69) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 | |
| SCHEMBL1107029 | 0.80 | PTGDR (0.59) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 | |
| SCHEMBL2703971 | 0.80 | TSHR (0.62) | LMNATRPV4TSHRSMN1; SMN2HTT | |
| SCHEMBL5007025 | 0.79 | GAA (0.62) | PTGDRPTGDR2LMNASMN1; SMN2GAA | |
| SCHEMBL10498551 | 0.79 | TRPV4 (0.53) | LMNATRPV4TSHRSMN1; SMN2HTT | |
| SCHEMBL4627361 | 0.79 | PTGDR (0.58) | PTGDRPTGDR2LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |