Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9349762 | 0.91 | SIGMAR1 (0.70) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL28760322 | 0.88 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Demelverine SCHEMBL1516521 | 0.85 | SIGMAR1 (0.76) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6974866 | 0.85 | SIGMAR1 (0.72) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL11134428 | 0.84 | SIGMAR1 (0.96) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9768687 | 0.83 | SIGMAR1 (0.73) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11613125 | 0.83 | AOC3 (0.56) | SIGMAR1AOC3TMEM97 | |
| SCHEMBL11922685 | 0.82 | SIGMAR1 (0.72) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7371550 | 0.82 | SIGMAR1 (1.00) | SIGMAR1TAAR1 | |
| SCHEMBL2058653 | 0.82 | SIGMAR1 (0.65) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476778-B | Modified conjugated diene polymer, modified conjugated diene polymer composition, tire, and method for producing modified conjugated diene polymer | 日本弹性体株式会社 | 2021-05-11 | — | — | CN | disclosed |
| CN-107250172-B | Modified conjugated diene polymer, method for producing same, and modified conjugated diene polymer composition | 旭化成株式会社 | 2021-04-09 | — | — | CN | disclosed |
| CN-109384982-B | Modified conjugated diene polymer composition and tire | 旭化成株式会社 | 2020-11-17 | — | — | CN | disclosed |
| EP-2906202-A1 | ORAL DRUG DELIVERY FORMULATIONS | Odidi, Isa (CA) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014059512-A1 | ORAL DRUG DELIVERY FORMULATIONS | ODIDI ISA (CA) | 2014-04-24 | — | — | WO | disclosed |
| EP-0699182-A1 | CYCLOPROPYLACETONITRILE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS DRUGS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1996-03-06 | — | — | EP | disclosed |
| WO-1995025087-A1 | CYCLOPROPYLACETONITRILE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS DRUGS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1995-09-21 | — | — | WO | disclosed |
| EP-0231003-B1 | BASIC SUBSTITUTED PHENYLACETONITRILES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-4968717-A | SEROTONIN-AND CALCIUM-ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0231003-A2 | Basic substituted phenylacetonitriles, their preparation and medicaments containing them | BASF Aktiengesellschaft (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0147707-B1 | 1,7-DIPHENYL-3-METHYLAZA-7-CYANO-8-METHYLNONANE USEFUL IN COMBATING DISEASES | BASF Aktiengesellschaft (DE) | 1987-03-18 | — | — | EP | disclosed |
| US-4596820-A | Antiischemic agents | BASF AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | disclosed |
| EP-0147707-A2 | 1,7-Diphenyl-3-methylaza-7-cyano-8-methylnonane useful in combating diseases | BASF Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |
| US-4127588-A | Sulphur containing derivatives | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4073797-A | CORONARY DILATOR | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4003914-A | DITHIANE AND DISULFONE CORONARY DILATING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |