Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.72 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9349762 | 0.91 | SIGMAR1 (0.70) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12902332 | 0.90 | SIGMAR1 (0.88) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28760322 | 0.88 | SIGMAR1 (0.63) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11133953 | 0.86 | SIGMAR1 (0.96) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7359447 | 0.85 | SIGMAR1 (0.70) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8096630 | 0.84 | SIGMAR1 (1.00) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18773747 | 0.82 | SIGMAR1 (0.86) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7972498 | 0.81 | SIGMAR1 (0.72) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6968328 | 0.81 | SIGMAR1 (0.72) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11104325 | 0.81 | SIGMAR1 (0.72) | SIGMAR1AOC3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |