Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17272740 | 0.88 | HTR1A (0.52) | HTR1ASIGMAR1 | |
| SCHEMBL17272705 | 0.83 | HTR1A (0.56) | HTR1ASIGMAR1 | |
| SCHEMBL7437505 | 0.83 | HTR1A (0.47) | HTR1ASIGMAR1 | |
| SCHEMBL17272733 | 0.83 | HTR1A (0.57) | HTR1ASIGMAR1 | |
| SCHEMBL15865440 | 0.82 | HTR1A (0.63) | HTR1ASIGMAR1 | |
| SCHEMBL7430039 | 0.81 | HTR1A (0.51) | HTR1ASIGMAR1 | |
| SCHEMBL15870257 | 0.80 | HTR1A (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL17272720 | 0.80 | HTR1A (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL15865438 | 0.80 | HTR1A (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL7366546 | 0.79 | SIGMAR1 (0.62) | HTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028157-A1 | NOVEL PIPERIDINE DERIVATIVES 4-SUBSTITUTED BY AN IMIDAZOLIDIN-2-ON-1-YL-ETHYL, TETRAHYDROPYRIMIDIN-2-ON-1-YL-ETHYL AND 1,3-DIAZEPIN-2-ON-1-YL-ETHYL GROUP, AND USE THEREOF AS α2-ADRENERGIC RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |