Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746372 | 0.81 | MAOA (0.60) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL28198664 | 0.77 | MAOA (0.62) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL7237933 | 0.77 | MAOA (0.52) | MAOAADRB2KDM4EALDH1A1GLA | |
| SCHEMBL6893811 | 0.76 | MAOA (0.69) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL5749472 | 0.76 | MAOA (0.61) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL5745354 | 0.76 | MAOA (0.61) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL6859087 | 0.76 | MAOA (0.60) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL7238515 | 0.76 | MAOA (0.50) | MAOAADRB2KDM4EALDH1A1GLA | |
| SCHEMBL5749134 | 0.75 | MAOA (0.59) | MAOA | |
| SCHEMBL5748462 | 0.75 | MAOA (0.59) | MAOAKDM4EALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495005-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | NATIONAL SCIENCE COUNCIL (TW) | 1996-02-27 | — | — | US | disclosed |