Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | PGAM1 | P18669 | 3/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746390 | 0.86 | MAOA (0.56) | MAOACYP2A6XDH | |
| SCHEMBL5749002 | 0.86 | MAOA (0.56) | MAOACYP2A6NPC1TOP2A | |
| SCHEMBL6893811 | 0.85 | MAOA (0.69) | MAOACYP2A6PGAM1ALDH1A1KDM4E | |
| SCHEMBL7381861 | 0.85 | XDH (0.60) | MAOAALDH1A1MAPTXDH | |
| SCHEMBL7425703 | 0.85 | XDH (0.60) | MAOAALDH1A1MAPTXDH | |
| SCHEMBL5746372 | 0.84 | MAOA (0.60) | MAOACYP2A6PGAM1KCNA3ALDH1A1 | |
| SCHEMBL5747126 | 0.84 | MAOA (0.57) | MAOACYP2A6ALDH1A1KDM4ENPC1 | |
| SCHEMBL5748795 | 0.84 | HTR1B (0.58) | MAOACYP2A6ALDH1A1KDM4ENPC1 | |
| SCHEMBL5798486 | 0.84 | XDH (0.65) | MAOAALDH1A1MAPTXDH | |
| SCHEMBL5749070 | 0.84 | MAOA (0.57) | MAOACYP2A6NPC1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557892-B | A kind of mangiferin unit point derivative and its production and use | 北京大学 | 2018-01-02 | — | — | CN | disclosed |