SCHEMBL7359702

SCHEMBL7359702

CC(C)(C)OC(=O)N1CCC(C2CCN(c3cc(C(=O)O)ccc3C(=O)O)CC2)CC1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.61
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2945397 0.83 GPR119 (0.81) GPR119KMT2A
SCHEMBL7356261 0.80 GPR119 (0.69) GPR119
SCHEMBL5223304 0.79 CKS1B (0.49) KMT2A
SCHEMBL8506021 0.78 GPR119 (0.67) GPR119
SCHEMBL20231074 0.76 GPR119 (0.55) GPR119KMT2A
SCHEMBL3486768 0.76 GPR119 (1.00) GPR119
SCHEMBL15285820 0.76 BACE1 (0.53) GPR119
SCHEMBL3486856 0.76 GPR119 (1.00) GPR119KMT2A
SCHEMBL17756946 0.75 GPR119 (0.47) GPR119KMT2A
SCHEMBL30776715 0.75 ALDH1A1 (0.50) GPR119KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900422-A Fibrinogen receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-05-04 US disclosed
WO-1996019221-A1 FIBRINOGEN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-06-27 WO disclosed