Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486768 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL8695331 | 0.81 | MAPT (0.52) | GPR119 | |
| SCHEMBL7359702 | 0.80 | GPR119 (0.61) | GPR119 | |
| SCHEMBL2945397 | 0.79 | GPR119 (0.81) | GPR119 | |
| SCHEMBL310117 | 0.78 | GPR119 (0.67) | GPR119 | |
| SCHEMBL2191425 | 0.77 | GPR119 (0.57) | GPR119 | |
| SCHEMBL29805245 | 0.77 | GPR119 (0.57) | GPR119 | |
| SCHEMBL3486880 | 0.77 | GPR119 (1.00) | GPR119 | |
| SCHEMBL3486806 | 0.77 | GPR119 (0.78) | GPR119 | |
| SCHEMBL31220479 | 0.76 | ALDH1A1 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037343-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| US-5900422-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-05-04 | — | — | US | disclosed |
| EP-0796098-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0794779-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0796098-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| EP-0794779-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996019221-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019223-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |