Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.41 |
| ▸ | FEN1 | P39748 | 13/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358633 | 0.90 | ALOX5AP (0.43) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL7365001 | 0.87 | ALOX5AP (0.42) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL7363801 | 0.77 | MMP3 (0.43) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL7459611 | 0.76 | MMP3 (0.44) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL7368049 | 0.75 | F2 (0.59) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL7459605 | 0.74 | F2 (0.59) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL5885954 | 0.74 | NR3C1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL7454504 | 0.73 | ALOX5AP (0.38) | ALOX5APFEN1 | |
| SCHEMBL7057459 | 0.72 | RORC (0.44) | ALOX5APFEN1F10 | |
| SCHEMBL5885956 | 0.72 | ALOX5AP (0.41) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |