SCHEMBL7364852

SCHEMBL7364852

COC(=O)COc1ccc(N2CCC(OCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 17/20 0.51
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8473888 0.87 GPR119 (0.68) GPR119
SCHEMBL8473886 0.87 GPR119 (0.68) GPR119
SCHEMBL7366689 0.87 GPR119 (0.47) GPR119MAPT
SCHEMBL7369003 0.85 GPR119 (0.50) GPR119MAPT
SCHEMBL8474377 0.85 GPR119 (0.50) GPR119MAPT
SCHEMBL7365948 0.84 YAP1 (0.56) GPR119
SCHEMBL7363874 0.84 GPR119 (0.58) GPR119
SCHEMBL7359036 0.84 MAPT (0.49) GPR119MAPT
SCHEMBL7358222 0.84 GPR119 (0.51) GPR119MAPT
SCHEMBL7369010 0.84 MAPT (0.59) GPR119MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994356-A ANTICOAGULANT KARL THOMAE (DE) 1999-11-30 US disclosed
EP-0892783-A1 CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION Dr. Karl Thomae GmbH (DE) 1999-01-27 EP disclosed
WO-1997037975-A1 CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION DR. KARL THOMAE GMBH (DE) 1997-10-16 WO disclosed