Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354083 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TSHREPHX1EPHX2 | |
| SCHEMBL7360252 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TSHREPHX1EPHX2 | |
| SCHEMBL7390348 | 0.79 | HRH3 (0.41) | ALDH1A1BTK | |
| SCHEMBL7390351 | 0.79 | HRH3 (0.41) | ALDH1A1BTK | |
| SCHEMBL8417022 | 0.75 | RORC (0.38) | ALDH1A1GAABTKMAPT | |
| SCHEMBL8417020 | 0.75 | RORC (0.38) | ALDH1A1GAABTKMAPT | |
| SCHEMBL7353734 | 0.74 | TP53 (0.40) | SMN1; SMN2ALDH1A1TP53POLBGAA | |
| SCHEMBL7357782 | 0.72 | TP53 (0.44) | SMN1; SMN2ALDH1A1EPHX1TP53MAPT | |
| SCHEMBL22657540 | 0.67 | TP53 (0.55) | SMN1; SMN2ALDH1A1TP53POLBGAA | |
| SCHEMBL25953781 | 0.67 | TP53 (0.55) | SMN1; SMN2ALDH1A1TP53POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | claimed |