Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 7/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18553802 | 0.87 | HTR6 (0.61) | HTR6LMNAHPGDRIPK2NOD2 | |
| SCHEMBL5851742 | 0.78 | HTR6 (0.64) | HTR6LMNARIPK2NOD2ACVR1 | |
| Hydrochloric Acid SCHEMBL7001932 | 0.77 | HTR6 (0.62) | HTR6LMNARIPK2NOD2ACVR1 | |
| SCHEMBL14356050 | 0.76 | PARP14 (0.45) | HTR6LMNAADRB1BRD4 | |
| SCHEMBL8781158 | 0.76 | HTR6 (0.61) | HTR6LMNARIPK2NOD2ACVR1 | |
| SCHEMBL7364830 | 0.75 | TGFBR1 (0.54) | LMNAALDH1A1NAMPT | |
| SCHEMBL9502908 | 0.74 | HPGD (0.52) | LMNAHPGDKDM4EALDH1A1AR | |
| SCHEMBL9156206 | 0.73 | HPGD (0.60) | LMNAHPGDKDM4EALDH1A1AR | |
| SCHEMBL10192137 | 0.73 | HPGD (0.60) | LMNAHPGDKDM4EALDH1A1AR | |
| SCHEMBL9742229 | 0.71 | ADRB1 (0.56) | HTR6LMNAKDM4EALDH1A1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |