Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 13/20 | 0.54 |
| ▸ | METAP1 | P53582 | 9/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974081 | 0.87 | ANPEP (0.49) | METAP2METAP1ANPEPMEN1MAPT | |
| SCHEMBL6489865 | 0.79 | METAP2 (0.83) | METAP2METAP1 | |
| SCHEMBL16899278 | 0.77 | CARM1 (0.60) | ANPEPMEN1MAPTKMT2A | |
| SCHEMBL16908240 | 0.77 | CARM1 (0.60) | ANPEPMEN1MAPTKMT2A | |
| SCHEMBL4317560 | 0.76 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL4403373 | 0.75 | ANPEP (0.61) | ANPEPMEN1MAPTKMT2A | |
| SCHEMBL7356908 | 0.75 | METAP2 (0.70) | METAP2METAP1 | |
| SCHEMBL6485389 | 0.75 | METAP2 (0.69) | METAP2METAP1MEN1KMT2A | |
| SCHEMBL18812522 | 0.75 | ANPEP (0.55) | ANPEPMEN1MAPTKMT2A | |
| SCHEMBL16908117 | 0.75 | ANPEP (0.55) | ANPEPMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | disclosed |