Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.69 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.69 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.69 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359904 | 0.86 | GAA (0.69) | PTPN7PTPN12PTPN22KMT2ABCL9 | |
| SCHEMBL7364945 | 0.85 | KMT2A (0.64) | PTPN7PTPN12PTPN22ENPP2SMN1; SMN2 | |
| SCHEMBL27542011 | 0.84 | PTPN7 (0.67) | PTPN7PTPN12PTPN22NPC1RAB9A | |
| SCHEMBL11605368 | 0.83 | PTPN7 (0.69) | PTPN7PTPN12PTPN22SMN1; SMN2KMT2A | |
| SCHEMBL9363100 | 0.82 | PTPN7 (0.64) | PTPN7PTPN12PTPN22ENPP2NPC1 | |
| SCHEMBL7359954 | 0.78 | PTPN7 (0.74) | PTPN7PTPN12PTPN22SMN1; SMN2KMT2A | |
| SCHEMBL8832017 | 0.77 | GAA (0.66) | PTPN7PTPN12PTPN22KMT2ABCL9 | |
| SCHEMBL7357068 | 0.76 | PTPN7 (0.72) | PTPN7PTPN12PTPN22NPC1RAB9A | |
| SCHEMBL11157408 | 0.76 | ALDH1A1 (0.67) | ENPP2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6865567 | 0.76 | MAPT (0.59) | PTPN7PTPN12PTPN22RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413750-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| WO-1989010920-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1989-11-16 | — | — | WO | disclosed |