Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.54 |
| ▸ | F10 | P00742 | 10/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.54 |
| ▸ | PLAU | P00749 | 5/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 5/20 | 0.43 |
| ▸ | F3 | P13726 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366139 | 0.98 | F10 (0.53) | F2F10PRSS1PLAUPLG | |
| SCHEMBL8909375 | 0.93 | F10 (0.53) | F2F10PRSS1PLAUPLG | |
| SCHEMBL7358748 | 0.89 | WDR5 (0.50) | F2F10PRSS1PLAUKLKB1 | |
| SCHEMBL8908041 | 0.88 | F10 (0.53) | F2F10PRSS1 | |
| SCHEMBL7364511 | 0.83 | F10 (0.57) | F2F10PRSS1 | |
| SCHEMBL8483349 | 0.80 | F2 (0.43) | F2F10PRSS1PLAUPLG | |
| SCHEMBL8443655 | 0.79 | F10 (0.43) | F2F10PRSS1PLAUPLG | |
| SCHEMBL7360640 | 0.77 | PLAU (0.56) | F2F10PRSS1PLAUPLG | |
| SCHEMBL8438856 | 0.76 | F10 (0.49) | F2F10PRSS1 | |
| SCHEMBL8908116 | 0.76 | F10 (0.49) | F2F10PRSS1PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848708-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-06-24 | — | — | EP | claimed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | claimed |
| WO-1996038421-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-12-05 | — | — | WO | claimed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |