Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PROC | P04070 | 2/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438856 | 0.92 | F10 (0.49) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8909063 | 0.83 | PRSS1 (0.43) | F10PLGPRSS1F2PLAT | |
| SCHEMBL7358748 | 0.80 | WDR5 (0.50) | F10PRSS1WDR5F2PLAU | |
| SCHEMBL7364511 | 0.79 | F10 (0.57) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8908041 | 0.78 | F10 (0.53) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7366139 | 0.78 | F10 (0.53) | F10PLGPRSS1F2PLAU | |
| SCHEMBL8438863 | 0.77 | F10 (0.48) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7360668 | 0.76 | F2 (0.54) | F10PLGPRSS1F2PLAU | |
| SCHEMBL8909375 | 0.74 | F10 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL3347284 | 0.72 | HSP90AA1 (0.54) | F10PLGPROCPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |