Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.52 |
| ▸ | F2 | P00734 | 10/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364860 | 0.94 | F10 (0.48) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL7368084 | 0.79 | F10 (0.48) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL7368630 | 0.77 | F10 (0.50) | F10F2PRSS1 | |
| SCHEMBL7379216 | 0.73 | ITGB3 (0.84) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL9710595 | 0.72 | ITGB3 (0.84) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL7359507 | 0.70 | F10 (0.57) | F10F2PRSS1 | |
| SCHEMBL289137 | 0.69 | F10 (0.57) | F10F2PRSS1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7460186 | 0.68 | F10 (0.51) | F10F2PRSS1TMPRSS6 | |
| SCHEMBL7118443 | 0.68 | ITGB3 (0.64) | F10F2PRSS1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7361309 | 0.68 | F10 (0.98) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |