Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.57 |
| ▸ | F2 | P00734 | 14/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7460186 | 0.94 | F10 (0.51) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7458383 | 0.82 | F10 (0.55) | F10F2PRSS1 | |
| SCHEMBL7364895 | 0.82 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL7360591 | 0.79 | F10 (0.67) | F10F2PRSS1 | |
| SCHEMBL4130181 | 0.75 | CPA3 (0.47) | — | |
| SCHEMBL27587442 | 0.75 | CPA3 (0.47) | — | |
| SCHEMBL7359525 | 0.73 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7361309 | 0.71 | F10 (0.98) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8347404 | 0.71 | F2 (0.55) | F10F2PRSS1 | |
| SCHEMBL7360769 | 0.70 | F10 (0.52) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |