Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.50 |
| ▸ | F2 | P00734 | 16/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368084 | 0.89 | F10 (0.48) | F10F2PRSS1 | |
| SCHEMBL7360769 | 0.77 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7364860 | 0.71 | F10 (0.48) | F10F2PRSS1 | |
| SCHEMBL7368632 | 0.69 | F2 (0.51) | F10F2PRSS1F7 | |
| SCHEMBL11490287 | 0.68 | EPHX1 (0.42) | — | |
| SCHEMBL7454445 | 0.67 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL7403326 | 0.65 | APAF1 (0.50) | — | |
| SCHEMBL14131793 | 0.65 | F10 (0.68) | F10F2PRSS1 | |
| SCHEMBL11490284 | 0.64 | KMT2A (0.41) | — | |
| SCHEMBL7360130 | 0.63 | F10 (0.58) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |