Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370924 | 0.83 | PPARG (0.42) | TP53TSHRPPARGHTR2A | |
| SCHEMBL16766773 | 0.74 | PPARG (0.42) | TP53TSHRPPARGHTR2A | |
| SCHEMBL8727428 | 0.72 | ESR1 (0.39) | TSHR | |
| SCHEMBL6878776 | 0.70 | MEN1 (0.53) | TP53TSHRS1PR1S1PR5S1PR3 | |
| SCHEMBL9695400 | 0.68 | FFAR1 (0.54) | TP53TSHRS1PR1S1PR5S1PR3 | |
| SCHEMBL7604793 | 0.68 | FFAR1 (0.54) | TP53TSHRS1PR1S1PR5S1PR3 | |
| SCHEMBL9441318 | 0.68 | FFAR1 (0.54) | TP53TSHRS1PR1S1PR5S1PR3 | |
| SCHEMBL15085356 | 0.68 | BRD4 (0.44) | PPARGHTR2A | |
| SCHEMBL9251201 | 0.67 | L3MBTL1 (0.37) | TP53TSHRPPARGHTR2A | |
| SCHEMBL9251200 | 0.67 | L3MBTL1 (0.37) | TP53TSHRPPARGHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |