Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360913 | 1.00 | ALDH1A1 (0.42) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7356489 | 0.91 | POLB (0.44) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7356481 | 0.91 | POLB (0.44) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7349164 | 0.82 | PDE4B (0.47) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7359063 | 0.82 | PDE4B (0.57) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7944333 | 0.82 | PDE4B (0.47) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7940588 | 0.82 | PDE4B (0.57) | ALDH1A1POLBPELI1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7359055 | 0.81 | PDE4B (0.56) | ALDH1A1POLBPELI1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7359060 | 0.81 | PDE4B (0.56) | ALDH1A1POLBPELI1MAPTNPC1 | |
| SCHEMBL7941640 | 0.76 | MAPT (0.47) | ALDH1A1POLBPELI1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |