Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.60 |
| ▸ | MMP8 | P22894 | 8/20 | 0.60 |
| ▸ | MMP14 | P50281 | 3/20 | 0.60 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309285 | 0.98 | MMP9 (0.60) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL8305171 | 0.98 | MMP9 (0.60) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL8305167 | 0.89 | MMP9 (0.58) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL8309283 | 0.89 | MMP9 (0.58) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL7361887 | 0.86 | MMP9 (0.55) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL7353746 | 0.86 | MMP9 (0.55) | MMP9MMP8MMP14GPR139PSMB5 | |
| SCHEMBL7361179 | 0.85 | MME (0.53) | — | |
| SCHEMBL7354151 | 0.84 | CTSL (0.46) | MMP9MMP8MMP14 | |
| SCHEMBL7361514 | 0.84 | BACE1 (0.48) | MMP8PSMB5MEN1KMT2AMAPT | |
| SCHEMBL7355198 | 0.82 | MEN1 (0.55) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |