Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSE | P14091 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175304 | 0.89 | KLK7 (0.40) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL2175307 | 0.89 | KLK7 (0.40) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7962411 | 0.89 | KLK7 (0.40) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL5833363 | 0.89 | KLK7 (0.40) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL9842023 | 0.86 | LMNA (0.38) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7270587 | 0.81 | KLK7 (0.41) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7270189 | 0.79 | KLK7 (0.38) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7279530 | 0.79 | KLK7 (0.38) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7270193 | 0.79 | KLK7 (0.38) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7279540 | 0.79 | KLK7 (0.38) | MAPTSMN1; SMN2ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |