Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 12/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HAT1 | O14929 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | MAP2 | P11137 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357973 | 0.76 | ALDH1A1 (0.41) | CXCR2FFAR1CYP2C9MAP2 | |
| SCHEMBL7338789 | 0.66 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL5831340 | 0.65 | IAPP (0.54) | FFAR1 | |
| SCHEMBL28050985 | 0.63 | CYP2A6 (0.50) | FFAR1 | |
| SCHEMBL7354262 | 0.62 | PTGS1 (0.42) | FFAR1CYP2C9 | |
| SCHEMBL7424087 | 0.62 | ALDH1A1 (0.47) | FFAR1CYP2C9 | |
| Hydrochloric Acid SCHEMBL7358454 | 0.61 | F2 (0.35) | — | |
| SCHEMBL7362233 | 0.61 | ALDH1A1 (0.47) | CYP2C9 | |
| SCHEMBL7353853 | 0.60 | ALDH1A1 (0.48) | CYP2C9 | |
| SCHEMBL7358200 | 0.60 | USP14 (0.41) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |