SCHEMBL8747161

SCHEMBL8747161

O=C(Oc1ccc(OC(=O)N2CC2)cc1)N1CC1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.79
POLB P06746 1/20 0.79
KMT2A Q03164 7/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
MEN1 O00255 5/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
LMNA P02545 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
MAPT P10636 2/20 0.59
HTT P42858 2/20 0.59
MGLL Q99685 1/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.56
TSHR P16473 1/20 0.55
ALOX15 P16050 1/20 0.54
CASP3 P42574 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11882343 0.89 MGLL (0.72) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL8747418 0.84 RAB9A (0.69) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL20278845 0.84 ALDH1A1 (0.59) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL15134826 0.83 CYP1A2 (0.69) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL10053020 0.83 MAPT (0.60) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL25224294 0.82 ALDH1A1 (0.79) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL8235480 0.82 ALDH1A1 (0.79) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL22031548 0.82 ALDH1A1 (0.79) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL22031542 0.82 ALDH1A1 (0.72) ALDH1A1POLBKMT2ASMN1; SMN2MEN1
SCHEMBL7179259 0.82 ALDH1A1 (0.79) ALDH1A1POLBKMT2ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP claimed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP claimed
EP-0526072-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-09-13 EP claimed
EP-0514807-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-08-23 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5384303-A Heat sensitive elements for color images with stabilizers NEW OJI PAPER CO., LTD. (JP) 1995-01-24 US claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5312796-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-17 US claimed
US-5246906-A Sulfonyl-urea or -thiourea color developer, oil and plasticizer resistant, storage stable OJI PAPER CO., LTD. (JP) 1993-09-21 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
EP-0526072-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-02-03 EP claimed
EP-0514807-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-25 EP claimed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP disclosed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP disclosed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP disclosed
EP-0514807-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-25 EP disclosed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP disclosed