Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360070 | 0.91 | KDM4E (0.44) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL7474561 | 0.80 | KDM4E (0.36) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL7362334 | 0.77 | KDM4E (0.47) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL7366837 | 0.73 | KDM4E (0.41) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL7228410 | 0.70 | MAPT (0.56) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL7366904 | 0.69 | KDM4E (0.49) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL8081069 | 0.69 | TNFSF11 (0.56) | KDM4EMAPTALDH1A1GAABLM | |
| SCHEMBL19006596 | 0.68 | PIM1 (0.42) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL29352103 | 0.68 | ADORA3 (0.48) | KDM4EMAPTALDH1A1GAARECQL | |
| SCHEMBL2776573 | 0.67 | POLB (0.57) | KDM4EMAPTALDH1A1GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | claimed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | claimed |
| US-5977077-A | PARASITICIDES; ANTIPROTOZOA AGENT | INTERLAB CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |