Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366904 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL7360070 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL7361090 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL7474561 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL7365521 | 0.72 | MAPT (0.56) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL19006596 | 0.72 | PIM1 (0.42) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL6193853 | 0.69 | HTT (0.54) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL8489585 | 0.67 | HTT (0.48) | KDM4EALDH1A1MAPTRECQLTDP1 | |
| SCHEMBL16747885 | 0.66 | KDM4E (0.50) | KDM4EALDH1A1MAPTTDP1GAA | |
| SCHEMBL28794942 | 0.65 | ABCB11 (0.47) | KDM4EALDH1A1MAPTRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | disclosed |