Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366837 | 0.85 | KDM4E (0.41) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL30998123 | 0.76 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL7235919 | 0.73 | KDM4E (0.49) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL16747885 | 0.71 | KDM4E (0.50) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL914221 | 0.70 | MAPT (0.52) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL29350633 | 0.69 | MAPK1 (0.62) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL7361090 | 0.69 | KDM4E (0.47) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL7360070 | 0.69 | KDM4E (0.44) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL6688920 | 0.68 | HTT (0.56) | KDM4EMAPTALDH1A1TDP1BLM | |
| SCHEMBL5212814 | 0.68 | MAPK1 (0.71) | KDM4EMAPTALDH1A1TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | disclosed |