Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.48 |
| ▸ | MMP8 | P22894 | 11/20 | 0.48 |
| ▸ | MMP1 | P03956 | 11/20 | 0.48 |
| ▸ | MMP9 | P14780 | 10/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361277 | 1.00 | MMP2 (0.48) | MMP2MMP8MMP1MMP9CTRB1 | |
| SCHEMBL7918687 | 0.83 | CTRB1 (0.58) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL30754693 | 0.83 | CTRB1 (0.58) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL27280340 | 0.79 | CTRB1 (0.60) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL24513611 | 0.79 | CTRB1 (0.64) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL11167627 | 0.79 | CTRB1 (0.64) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL11167632 | 0.79 | CTRB1 (0.64) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL11450738 | 0.79 | CTRB1 (0.64) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL7106091 | 0.79 | CTRB1 (0.64) | CTRB1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL7920393 | 0.78 | CTRB1 (0.58) | CTRB1NPSR1TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |