Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912499 | 0.87 | ALDH1A1 (0.45) | ATMALDH1A1LMNAGLATHRB | |
| SCHEMBL9715661 | 0.85 | POLB (0.48) | ATMALDH1A1LMNAGLAPIN1 | |
| SCHEMBL3725043 | 0.82 | ATM (0.63) | ATMALDH1A1LMNAGLATHRB | |
| SCHEMBL2734812 | 0.82 | ATM (0.63) | ATMALDH1A1LMNAGLATHRB | |
| SCHEMBL8724389 | 0.82 | ATM (0.63) | ATMALDH1A1LMNAGLATHRB | |
| Hydrochloric Acid SCHEMBL8724387 | 0.81 | ATM (0.61) | ATMALDH1A1LMNAGLATHRB | |
| Hydrochloric Acid SCHEMBL7327532 | 0.81 | ATM (0.61) | ATMALDH1A1LMNAGLATHRB | |
| SCHEMBL8337019 | 0.81 | ATM (0.50) | ATMALDH1A1LMNAGLATHRB | |
| Phosphoric Acid SCHEMBL27956600 | 0.81 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL2059140 | 0.80 | TACR1 (0.58) | ALDH1A1POLBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131813-B | Biocatalytic process for the preparation of substantially stereoisomerically pure fused bicyclic proline compounds | CODEXIS INC | 2014-07-30 | — | — | CN | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |