Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359457 | 0.94 | FFAR1 (0.45) | KCNN4KCNA5MEN1KMT2AUSP2 | |
| SCHEMBL7464056 | 0.91 | FFAR1 (0.43) | KCNN4KCNA5MEN1KMT2AUSP2 | |
| SCHEMBL7362630 | 0.87 | KCNH2 (0.47) | KCNN4KCNA5FFAR1MMP12MMP13 | |
| SCHEMBL7368444 | 0.84 | FFAR1 (0.41) | KCNN4KCNA5MEN1KMT2AUSP2 | |
| SCHEMBL7360603 | 0.81 | KCNH2 (0.45) | KCNN4KCNA5FFAR1 | |
| SCHEMBL7365143 | 0.78 | MMP12 (0.37) | KCNN4KCNA5FFAR1LMNAFFAR4 | |
| SCHEMBL7361445 | 0.75 | KCNN4 (0.42) | KCNN4KCNA5FFAR1LMNAFOLH1 | |
| SCHEMBL7361741 | 0.73 | KCNN4 (0.40) | KCNN4KCNA5MEN1KMT2AUSP2 | |
| SCHEMBL11312464 | 0.73 | KCNN4 (0.46) | KCNN4KCNA5MEN1KMT2AFFAR1 | |
| SCHEMBL7361441 | 0.72 | FFAR1 (0.44) | KCNN4KCNA5MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |