Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361444 | 0.94 | KCNN4 (0.46) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7464056 | 0.92 | FFAR1 (0.43) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7362630 | 0.88 | KCNH2 (0.47) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7368444 | 0.85 | FFAR1 (0.41) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7360603 | 0.82 | KCNH2 (0.45) | FFAR1KCNN4KCNA5 | |
| SCHEMBL7365143 | 0.79 | MMP12 (0.37) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7361445 | 0.72 | KCNN4 (0.42) | FFAR1KCNN4KCNA5MMP12MMP13 | |
| SCHEMBL7359475 | 0.71 | FFAR1 (0.56) | FFAR1MMP12MMP13FFAR4MEN1 | |
| SCHEMBL7359452 | 0.71 | PDCD1 (0.44) | FFAR1KCNN4KCNA5FFAR4KMT2A | |
| SCHEMBL21518478 | 0.70 | CHRNB2 (0.43) | MEN1KMT2ANPC1RORCMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |