Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361718 | 0.74 | KDM4E (0.54) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL3700170 | 0.74 | CNR2 (0.43) | TAAR1CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL7393751 | 0.74 | CSNK1E (0.42) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL13919551 | 0.71 | MAPT (0.53) | MAOASIGMAR1LAP3SMN1; SMN2PKM | |
| SCHEMBL27502071 | 0.69 | EPHX1 (0.52) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL22885976 | 0.69 | CYP1A2 (0.42) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL23752456 | 0.67 | SLC6A2 (0.61) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL6193282 | 0.67 | SLC6A2 (0.61) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL8091553 | 0.67 | SLC6A2 (0.61) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 | |
| SCHEMBL2232612 | 0.67 | SLC6A2 (0.61) | CSNK1ESLC6A2SLC6A3SLC6A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |