Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 4/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.51 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752456 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL29941240 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6191623 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6193282 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL2232612 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27535848 | 0.98 | SLC6A2 (0.59) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Bicarbonate SCHEMBL7838533 | 0.94 | SLC15A1 (0.56) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6575399 | 0.83 | SLC6A2 (0.57) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6580061 | 0.83 | SLC6A2 (0.57) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL22431194 | 0.82 | EPHX1 (0.58) | SLC6A2TAAR1MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| EP-1059285-A2 | Process for the preparation of 1,3-diamino-2-propanol and 1,3-diamino-2-propanone derivatives | Pharm-Eco Laboratories, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |