Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592046 | 1.00 | ALDH1A1 (0.51) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL29638170 | 0.90 | ALDH1A1 (0.55) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL15623775 | 0.90 | ALDH1A1 (0.62) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL4027352 | 0.88 | PLA2G2A (0.61) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL27927721 | 0.87 | FOLH1 (0.49) | KMT2AFOLH1TSHR | |
| SCHEMBL4075415 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL4075414 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL15680095 | 0.85 | FOLH1 (0.60) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL9664224 | 0.83 | PLA2G2A (0.69) | ALDH1A1PLA2G2APLA2G5MEN1LMNA | |
| SCHEMBL7333737 | 0.83 | PLA2G2A (0.69) | ALDH1A1PLA2G2APLA2G5MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |