Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361741 | 0.75 | KCNN4 (0.40) | PRSS1TAAR1KCNN4KCNA5FFAR1 | |
| SCHEMBL7361441 | 0.75 | FFAR1 (0.44) | KCNN4KCNA5GFERFFAR1FFAR4 | |
| SCHEMBL7359452 | 0.73 | PDCD1 (0.44) | F2PRSS1PRSS2PRSS3KCNN4 | |
| SCHEMBL7368049 | 0.72 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7462659 | 0.72 | FFAR1 (0.44) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7464051 | 0.70 | PDCD1 (0.42) | F2PRSS1PRSS2PRSS3KCNN4 | |
| SCHEMBL7056650 | 0.70 | KCNN4 (0.45) | KCNN4KCNA5MEP1AMEP1BMCHR1 | |
| SCHEMBL7459672 | 0.69 | FFAR1 (0.41) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8113653 | 0.69 | ALDH1A1 (0.44) | KCNN4KCNA5MEP1AMEP1BMCHR1 | |
| SCHEMBL4269765 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |