Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462659 | 0.93 | FFAR1 (0.44) | FFAR1FFAR4F2PRSS1PRSS2 | |
| SCHEMBL7362467 | 0.87 | FFAR1 (0.53) | FFAR1FFAR4MEN1USP2KMT2A | |
| SCHEMBL7464051 | 0.80 | PDCD1 (0.42) | FFAR1FFAR4F2PRSS1PRSS2 | |
| SCHEMBL7359475 | 0.79 | FFAR1 (0.56) | FFAR1FFAR4MEN1USP2KMT2A | |
| Trifluoroacetic Acid SCHEMBL7454841 | 0.79 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7368439 | 0.78 | PDCD1 (0.40) | FFAR1FFAR4F2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7454448 | 0.77 | F2 (0.43) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7357492 | 0.76 | FFAR1 (0.47) | FFAR1FFAR4F2PRSS1PRSS2 | |
| SCHEMBL7362325 | 0.76 | FFAR1 (0.42) | FFAR1FFAR4F2PRSS1PRSS2 | |
| SCHEMBL3466545 | 0.73 | MMP12 (0.54) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |