Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982499 | 0.85 | KCNN4 (0.54) | KCNN4KCNA5MAOBFFAR1GFER | |
| SCHEMBL3830265 | 0.82 | KCNN4 (0.47) | KCNN4KCNA5MAOBFFAR1GFER | |
| SCHEMBL3345002 | 0.80 | MAPK1 (0.50) | KCNA5MAPK1MEN1KMT2A | |
| SCHEMBL6982511 | 0.77 | CRHBP (0.52) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL8106455 | 0.77 | KCNN4 (0.43) | KCNN4KCNA5MAOBFFAR1GFER | |
| SCHEMBL7057421 | 0.76 | FFAR1 (0.47) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL6476823 | 0.76 | KCNA5 (0.46) | KCNN4KCNA5GSK3BCLK1MEN1 | |
| SCHEMBL8117060 | 0.76 | FFAR1 (0.42) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL8120082 | 0.76 | FFAR1 (0.45) | KCNN4KCNA5MAOBFFAR1GFER | |
| SCHEMBL7357492 | 0.75 | FFAR1 (0.47) | KCNN4KCNA5MAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | KCNN4 4233/4885KCNA5 3355/4885MAOB 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.