Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | OGT | O15294 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520525 | 0.79 | CA2 (0.57) | CA2CNR1CA12CA9KMT2A | |
| SCHEMBL670176 | 0.78 | CA2 (0.56) | CA2CNR1CA12CA9MEN1 | |
| SCHEMBL30684143 | 0.78 | CA2 (0.56) | CA2CNR1CA12CA9MEN1 | |
| SCHEMBL3237494 | 0.77 | CA2 (0.62) | CA2CNR1CA12CA9KMT2A | |
| SCHEMBL31561597 | 0.77 | CA2 (0.62) | CA2CNR1CA12CA9KMT2A | |
| SCHEMBL28568569 | 0.77 | CA2 (0.71) | CA2CNR1CA12CA9MAPT | |
| SCHEMBL8960439 | 0.75 | CA2 (0.56) | CA2CNR1CA12CA9MAPT | |
| SCHEMBL4862702 | 0.75 | CA2 (0.56) | CA2CNR1CA12CA9MAPT | |
| SCHEMBL13542579 | 0.74 | CA2 (0.51) | TSHRCA2CNR1CA12CA9 | |
| SCHEMBL16797504 | 0.74 | MAPK1 (0.81) | MAPK1POLBTSHRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036611-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |