SCHEMBL736190

SCHEMBL736190

CCCCCCCCCCCCCCCCCCCCCC(=O)C(CC)CCCCN

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CES2 O00748 1/20 0.47
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
CPB2 Q96IY4 1/20 0.45
DNM1 Q05193 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115893 1.00 CA1 (0.47) CA1CA2CES2GNAI3GNAO1
SCHEMBL739218 0.95 CA2 (0.48) CA1CA2CES2
SCHEMBL115897 0.95 CA2 (0.48) CA1CA2CES2
SCHEMBL115454 0.95 CA2 (0.48) CA1CA2CES2
SCHEMBL9074791 0.91 CES2 (0.55) CA1CA2CES2
SCHEMBL8369201 0.87 CA2 (0.57) CA1CA2CES2
SCHEMBL22597505 0.86 CA2 (0.52) CA1CA2CES2GNAI3GNAO1
SCHEMBL13679327 0.85 CA2 (0.59) CA1CA2CES2
SCHEMBL736191 0.84 CES2 (0.48) CA2CES2DNM1MEN1KMT2A
SCHEMBL115894 0.84 CES2 (0.48) CA2CES2DNM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658508-B2 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2024-06-19 EP disclosed
EP-2658508-B1 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2021-06-16 EP disclosed
EP-2560606-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-08-23 EP disclosed
EP-2560608-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-04-05 EP disclosed
EP-2346481-B1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-08-31 EP disclosed
EP-2377513-B1 Colouring composition KAO GERMANY GMBH (DE) 2016-03-30 EP disclosed
EP-2346480-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2016-01-06 EP disclosed
US-8795391-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-08-05 US disclosed
US-8673022-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-03-18 US disclosed
US-8668746-B2 Two-part hair colouring composition KAO GERMANY GMBH (DE) 2014-03-11 US disclosed
EP-2377511-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 EP disclosed
EP-2377513-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 EP disclosed
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH 2011-10-06 US disclosed
US-20110197912-A1 COLORING COMPOSITION KPSS-KAO PROFESSIONAL SAL SERVICES GMBH 2011-08-18 US disclosed
EP-2346481-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 EP disclosed
EP-2346480-A2 COLOURING COMPOSITION KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 EP disclosed
WO-2010046077-A2 COLOURING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
WO-2010046080-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
EP-2177204-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
EP-2177205-A1 Composition for the permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110197912-A1 COLORING COMPOSITION KRT18, POLL, POLQ CA1 3409/4885CA2 3973/4885CES2 3339/4885
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR POLR1C, DRD3, DRD4 CA1 4111/4885CA2 4246/4885CES2 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.