Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763977 | 0.83 | CYP4F2 (0.33) | CYP4F2CYP4A11DGAT1NPSR1 | |
| SCHEMBL12140467 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL9720237 | 0.80 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL16660833 | 0.78 | DGAT1 (0.46) | CYP4F2CYP4A11DGAT1NPSR1CTSK | |
| SCHEMBL17540555 | 0.78 | CYP4F2 (0.44) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL7365156 | 0.77 | NAMPT (0.34) | DGAT1 | |
| SCHEMBL5747724 | 0.76 | CYP2C19 (0.47) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL1764252 | 0.75 | CYP4F2 (0.42) | CYP4F2CYP4A11DGAT1NPSR1CTSK | |
| SCHEMBL4462480 | 0.75 | POLB (0.39) | — | |
| SCHEMBL15537328 | 0.74 | CYP2C19 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407960-A | For cardiovascualr disorders, pain | SCHERING CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1991009840-A1 | MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |