Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764700 | 0.84 | CYP4F2 (0.49) | CYP4F2CYP4A11 | |
| SCHEMBL8280788 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL7362008 | 0.83 | CYP4F2 (0.35) | CYP4F2CYP4A11DGAT1NPSR1 | |
| SCHEMBL8280127 | 0.80 | CYP2C19 (0.44) | DGAT1 | |
| SCHEMBL21800623 | 0.76 | APP (0.37) | — | |
| SCHEMBL21749202 | 0.75 | L3MBTL1 (0.41) | — | |
| SCHEMBL16660833 | 0.74 | DGAT1 (0.46) | CYP4F2CYP4A11DGAT1NPSR1 | |
| SCHEMBL18548341 | 0.73 | DDB1 (0.41) | — | |
| SCHEMBL1764252 | 0.72 | CYP4F2 (0.42) | CYP4F2CYP4A11DGAT1NPSR1 | |
| SCHEMBL30736687 | 0.71 | CYP4F2 (0.41) | CYP4F2CYP4A11DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2018-11-20 | — | — | US | disclosed |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS (FR) | 2014-06-12 | — | — | US | disclosed |
| US-8703747-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2014-04-22 | — | — | US | disclosed |
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS | 2011-05-26 | — | — | US | disclosed |
| EP-0767794-B1 | PHOSPHINIC ACID DERIVATIVES | SCHERING CORP (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5476847-A | Treating cardiovascular, gastrointestinal, urogenital disorders | SCHERING CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | CYP4F2 2280/4885CYP4A11 1103/4885DGAT1 4098/4885 |
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | OPRM1, HRH3, HRH4 | CYP4F2 2255/4885CYP4A11 1224/4885DGAT1 4165/4885 |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | CYP4F2 2255/4885CYP4A11 1224/4885DGAT1 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.