Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225888 | 0.80 | S1PR2 (0.38) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL29953835 | 0.78 | SLC6A2 (0.42) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL29956660 | 0.78 | SLC6A2 (0.42) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL3264929 | 0.78 | SLC6A2 (0.42) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL6664634 | 0.76 | ENPEP (0.46) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL6666416 | 0.76 | ENPEP (0.46) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL28799207 | 0.75 | SLC22A6 (0.47) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL6371658 | 0.75 | GABRP (0.39) | S1PR2S1PR1ENPEPANPEPSLC6A2 | |
| SCHEMBL28990971 | 0.75 | CYP2D6 (0.48) | S1PR2S1PR1ENPEPANPEPGABRR1 | |
| SCHEMBL28202300 | 0.75 | GABRP (0.39) | S1PR2S1PR1ENPEPANPEPSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |