Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202300 | 0.80 | GABRP (0.39) | CYP2D6ALDH1A1ARG2S1PR2S1PR1 | |
| SCHEMBL6371658 | 0.80 | GABRP (0.39) | CYP2D6ALDH1A1ARG2S1PR2S1PR1 | |
| SCHEMBL26530470 | 0.78 | ALDH1A1 (0.50) | CYP2D6ALDH1A1ALOX15ARG2SLC6A2 | |
| SCHEMBL285355 | 0.77 | ARG2 (0.33) | ARG2S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL1225888 | 0.77 | S1PR2 (0.38) | CYP2D6S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL3264929 | 0.75 | SLC6A2 (0.42) | CYP2D6S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL29956660 | 0.75 | SLC6A2 (0.42) | CYP2D6S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL7362116 | 0.75 | S1PR2 (0.37) | CYP2D6S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL29953835 | 0.75 | SLC6A2 (0.42) | CYP2D6S1PR2S1PR1ENPEPANPEP | |
| SCHEMBL6666416 | 0.73 | ENPEP (0.46) | ALDH1A1S1PR2S1PR1ENPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118806759-A | Systemic formulations of pyridone derivatives for TG2 related diseases | 福尔克博士药物有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115867260-B | Systemic formulations of pyridone derivatives for celiac disease | 福尔克博士药物有限责任公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-115715187-B | Systemic formulations of pyridone derivatives for TG2 related diseases | 福尔克博士药物有限责任公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-115867260-A | Systemic formulations of pyridone derivatives for celiac disease | 福尔克博士药物有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115715187-A | Systemic formulations of pyridone derivatives for TG 2-related diseases | 福尔克博士药物有限责任公司 | 2023-02-24 | — | — | CN | disclosed |