Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183121 | 0.97 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7362170 | 0.95 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7357429 | 0.77 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8575965 | 0.75 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7018969 | 0.74 | CYP19A1 (0.44) | — | |
| SCHEMBL7364010 | 0.73 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9377344 | 0.72 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7058755 | 0.72 | DDB1 (0.42) | — | |
| SCHEMBL7355695 | 0.71 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7361217 | 0.71 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987006576-A1 | CALCIUM INDEPENDENT CAMP PHOSPHODIESTERASE INHIBITOR ANTIDEPRESSANT | PFIZER INC. (US) | 1987-11-05 | — | — | WO | disclosed |