Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370375 | 0.83 | KMT2A (0.54) | KMT2AMAPTPKMLMNASMN1; SMN2 | |
| SCHEMBL6189909 | 0.72 | KAT2B (0.50) | KMT2AMAPTPKMLMNAKAT2B | |
| SCHEMBL24993978 | 0.70 | KAT2B (0.63) | KMT2AMAPTPKMLMNAKAT2B | |
| SCHEMBL4464340 | 0.69 | KAT2B (0.56) | KMT2AMAPTPKMLMNAKAT2B | |
| SCHEMBL4964339 | 0.69 | HSD11B1 (0.61) | KMT2AHSD11B1DPP4MEN1NPC1 | |
| SCHEMBL4629395 | 0.69 | HSD11B1 (0.61) | KMT2AHSD11B1DPP4MEN1NPC1 | |
| SCHEMBL11544206 | 0.69 | KAT2B (0.65) | KMT2AMAPTPKMLMNAKAT2B | |
| SCHEMBL5767127 | 0.68 | PKM (0.61) | KMT2AMAPTPKMLMNAKAT2B | |
| Hydrochloric Acid SCHEMBL29238125 | 0.68 | HSD11B1 (0.60) | KMT2AHSD11B1DPP4MEN1NPC1 | |
| SCHEMBL5881547 | 0.68 | KAT2B (0.60) | KMT2AMAPTPKMLMNAKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |