SCHEMBL736223

SCHEMBL736223

Cc1oc(O)cc(=O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 4/20 0.37
TP53 P04637 3/20 0.37
PTGS1 P23219 3/20 0.37
PTGS2 P35354 3/20 0.37
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GAA P10253 2/20 0.37
ALOX15 P16050 2/20 0.37
RECQL P46063 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 5/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GLA P06280 1/20 0.37
RNASEH1 O60930 1/20 0.36
NQO1 P15559 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590278 0.81 PTGS1 (0.50) KDM4ELMNAMAPTTP53PTGS1
SCHEMBL18931211 0.79 PTGS1 (0.40) KDM4ELMNAMAPTTP53PTGS1
SCHEMBL8270272 0.76 RNASEH1 (0.46) KDM4ELMNAMAPTTP53PTGS1
SCHEMBL41818 0.74 KDM4E (0.42) KDM4ELMNAMAPTTP53PTGS1
SCHEMBL3555239 0.74 KDM4E (0.54) KDM4EMAPTPOLBL3MBTL1GAA
SCHEMBL8477207 0.71 KDM4E (0.46) KDM4ELMNAMAPTPOLBL3MBTL1
Acetic Acid SCHEMBL14990893 0.69 KDM4E (0.39) KDM4ELMNAMAPTPOLBL3MBTL1
SCHEMBL8482842 0.69 ALOX15 (0.49) KDM4EMAPTPOLBL3MBTL1GAA
SCHEMBL12351988 0.69
SCHEMBL18087493 0.67 PTGS1 (0.50) KDM4ELMNAMAPTTP53PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661465-B2 Fat-based confections comprising flavor components MARS INC (US) 2018-08-22 EP claimed
US-8137726-B2 Dulce de leche-flavored fat-based confection, method for making the same and confectionery candies making use of the same MARS INCORPORATED (US) 2012-03-20 US claimed
US-20110027442-A1 DULCE DE LECHE-FLAVORED FAT-BASED CONFECTION, METHOD FOR MAKING THE SAME AND CONFECTIONERY CANDIES MAKING USE OF THE SAME MARS INCORPORATED (US) 2011-02-03 US claimed
EP-1661465-B1 Fat-based confections comprising flavor components MARS INC (US) 2010-08-25 EP claimed
US-20090181123-A1 METHODS FOR ENHANCING WINE FLAVOR LA CAZE DANIEL 2009-07-16 US claimed
WO-2008157305-A2 METHODS FOR ENHANCING WINE FLAVOR LA CAZE DANIEL (US) 2008-12-24 WO claimed
US-20070202244-A1 DULCE DE LECHE-FLAVORED FAT-BASED CONFECTION, METHOD FOR MAKING THE SAME AND CONFECTIONERY CANDIES MAKING USE OF THE SAME MARS INCORPORATED (US) 2007-08-30 US claimed
EP-1661465-A1 Fat-based confections comprising flavor components Mars Incorporated (US) 2006-05-31 EP claimed
EP-1411778-A2 DULCE DE LECHE-FLAVORED FAT-BASED CONFECTION, METHOD FOR MAKING THE SAME AND CONFECTIONERY CANDIES MAKING USE OF THE SAME Mars Incorporated (US) 2004-04-28 EP claimed
US-20030031771-A1 Dulce de leche-flavored fat-based confection, method for making the same and confectionery candies making use of the same MARS INCORPORATED 2003-02-13 US claimed
WO-2003007725-A2 DULCE DE LECHE-FLAVORED FAT-BASED CONFECTION, METHOD FOR MAKING THE SAME AND CONFECTIONERY CANDIES MAKING USE OF THE SAME MARS INCORPORATED (US) 2003-01-30 WO claimed
EP-0422466-A1 Endermic preparation of external application Sansho Seiyaku Co., Ltd. (JP) 1991-04-17 EP claimed
EP-3682742-B1 ALLULOSE CARAMEL SAVANNA INGREDIENTS GMBH (DE) 2023-10-11 EP disclosed
CN-112352995-A Additive for improving sensory quality of cut stems and preparation method and application thereof 河南中烟工业有限责任公司 2021-02-12 CN disclosed
CN-107422051-B Method for on-line detection of pyrolysis gas-phase components of tobacco additive or tobacco material at different temperatures 上海烟草集团有限责任公司 2020-08-11 CN disclosed
EP-3682742-A1 ALLULOSE CARAMEL Pfeifer & Langen GmbH & Co. KG (DE) 2020-07-22 EP disclosed
US-5075299-A CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENTS MEIJI SEIKA KAISHA, LTD. (JP) 1991-12-24 US disclosed
EP-0422466-A1 Endermic preparation of external application Sansho Seiyaku Co., Ltd. (JP) 1991-04-17 EP disclosed
EP-0173401-B1 BUTTER-LIKE CONCENTRATE UNILEVER N.V. (NL) 1988-02-24 EP disclosed
US-4701335-A Butter-like concentrate LEVER BROTHERS COMPANY (US) 1987-10-20 US disclosed