SCHEMBL8477207

SCHEMBL8477207

CCCc1cc(=O)c(O)c(C)o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALOX15 P16050 2/20 0.41
ALDH1A1 P00352 4/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HIF1A Q16665 4/20 0.39
EPAS1 Q99814 4/20 0.39
STS P08842 1/20 0.38
LMNA P02545 1/20 0.37
ABCG2 Q9UNQ0 2/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSD17B3 P37058 1/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8482842 0.89 ALOX15 (0.49) KDM4EALOX15ALDH1A1POLBTDP1
SCHEMBL41818 0.85 KDM4E (0.42) KDM4EALOX15ALDH1A1POLBTDP1
SCHEMBL3555239 0.81 KDM4E (0.54) KDM4EALDH1A1POLBTDP1L3MBTL1
Acetic Acid SCHEMBL14990893 0.79 KDM4E (0.39) KDM4EALDH1A1POLBTDP1L3MBTL1
SCHEMBL2468840 0.73 IDH1 (0.54) KDM4EALDH1A1POLBSTSHTR2B
SCHEMBL3337458 0.71 KDM4E (0.65) KDM4EALOX15ALDH1A1POLBTDP1
SCHEMBL2590278 0.71 PTGS1 (0.50) KDM4EALOX15POLBL3MBTL1LMNA
SCHEMBL3922006 0.71 TLR8 (0.37) KDM4EALOX15ALDH1A1POLBHIF1A
SCHEMBL736223 0.71 KDM4E (0.45) KDM4EALOX15ALDH1A1POLBTDP1
SCHEMBL29895970 0.70 ELANE (0.47) KDM4EALOX15ALDH1A1HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114585699-A Self-stopping polishing composition and method CMC材料股份有限公司 2022-06-03 CN claimed
EP-3890694-A1 HAIR CARE COMPOSITION FOR CLEANSING AND REFRESHING THE HAIR AND THE SCALP The Procter & Gamble Company (US) 2021-10-13 EP claimed
CN-112996480-A Hair care compositions for cleansing and freshening hair and scalp 宝洁公司 2021-06-18 CN claimed
WO-2021081171-A1 SELF-STOPPING POLISHING COMPOSITION AND METHOD CMC MATERIALS, INC. (US) 2021-04-29 WO claimed
US-20210115301-A1 SELF-STOPPING POLISHING COMPOSITION AND METHOD Cabot Microelectronics Corporation nka CMC Materials, Inc. 2021-04-22 US claimed
WO-2020117729-A1 HAIR CARE COMPOSITION FOR CLEANSING AND REFRESHING THE HAIR AND THE SCALP THE PROCTER & GAMBLE COMPANY (US) 2020-06-11 WO claimed
US-20200170906-A1 HAIR CARE COMPOSITION FOR CLEANSING AND REFRESHING THE HAIR AND THE SCALP THE PROCTER & GAMBLE COMPANY 2020-06-04 US claimed
EP-4156943-A1 ANTIMICROBIAL COMPOSITIONS COMPRISING MALTOL Sharon Laboratories Ltd. (IL) 2023-04-05 EP disclosed
CN-110520493-B Self-stopping polishing composition and method for bulk oxide planarization CMC材料股份有限公司 2022-11-22 CN disclosed
CN-114585699-A Self-stopping polishing composition and method CMC材料股份有限公司 2022-06-03 CN disclosed
CN-113637412-A Self-stopping polishing composition and method for bulk oxide planarization 嘉柏微电子材料股份公司 2021-11-12 CN disclosed
EP-3890694-A1 HAIR CARE COMPOSITION FOR CLEANSING AND REFRESHING THE HAIR AND THE SCALP The Procter & Gamble Company (US) 2021-10-13 EP disclosed
CN-112996480-A Hair care compositions for cleansing and freshening hair and scalp 宝洁公司 2021-06-18 CN disclosed
WO-1999023089-A1 RECOVERY OF GAMMA-PYRONES CULTOR FOOD SCIENCE, INC. (US) 1999-05-14 WO disclosed
EP-0473764-A1 METAL COMPLEXES Hider, Robert Charles (GB) 1992-03-11 EP disclosed
WO-1991014664-A1 METAL COMPLEXES HIDER ROBERT CHARLES (GB) 1991-10-03 WO disclosed
US-4629586-A Hexynyl alkanoates and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-12-16 US disclosed
US-4539209-A ENHANCING TROPICAL FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-09-03 US disclosed
US-4465695-A FLAVOR, AROMA ENHANCERS FOR FOODS, VITAMINS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-08-14 US disclosed
US-4416902-A Flavoring with cyclohexenyl-beta-methyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200170906-A1 HAIR CARE COMPOSITION FOR CLEANSING AND REFRESHING THE HAIR AND THE SCALP SMURF1, SMURF2, DSG1 KDM4E 1414/4885ALOX15 897/4885ALDH1A1 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.